MOTS-c is a 16-amino-acid mitochondrial-derived peptide investigated for its involvement in cellular energy metabolism, metabolic stress responses, and AMPK-associated signaling. Encoded within the mitochondrial 12S rRNA region, MOTS-c provides a valuable research model for studying mitochondrial communication, glucose metabolism, and cellular adaptation to metabolic stress.
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino-acid mitochondrial-derived peptide investigated for its involvement in cellular energy regulation, metabolic signaling, and adaptive stress responses.
Encoded by a short open reading frame within the mitochondrial 12S ribosomal RNA region, MOTS-c represents an important research subject in mitochondrial biology and cellular metabolism.
Its discovery has contributed to scientific interest in mitochondrial-derived peptides as potential regulators of intracellular and intercellular communication.
Key Scientific Research Applications
1. Mitochondrial Communication Research
MOTS-c is investigated as a mitochondrial-derived signaling molecule potentially involved in communication between mitochondrial activity and nuclear regulatory pathways.
2. AMPK-Associated Metabolic Signaling
Experimental studies have associated MOTS-c with AMP-activated protein kinase (AMPK) signaling, a pathway involved in cellular energy sensing and metabolic adaptation.
3. Glucose Metabolism Research
Preclinical investigations examine MOTS-c-associated changes in glucose regulation, metabolic homeostasis, and cellular responses to altered energy availability.
4. Cellular Stress Response Research
Researchers investigate the potential role of MOTS-c in metabolic stress adaptation, including stress-associated nuclear localization and transcriptional regulation.
5. Metabolic Flexibility & Energy Homeostasis
MOTS-c is studied in experimental models exploring cellular metabolic flexibility, nutrient sensing, and energy balance.
Scientific Significance
MOTS-c represents an emerging area of mitochondrial peptide research. Its mitochondrial genetic origin and reported interactions with cellular metabolic pathways make it scientifically relevant to investigations of energy sensing, mitochondrial-nuclear communication, and stress-response biology.
Although preclinical findings are promising, the precise molecular mechanisms and broader biological significance of MOTS-c remain under investigation.
Research Use Only
For Research Use Only (RUO). Intended exclusively for laboratory research, analytical investigation, and scientific study.
Mots-c
$39.99 – $64.99Price range: $39.99 through $64.99
MOTS-c is a 16-amino-acid mitochondrial-derived peptide investigated for its involvement in cellular energy metabolism, metabolic stress responses, and AMPK-associated signaling. Encoded within the mitochondrial 12S rRNA region, MOTS-c provides a valuable research model for studying mitochondrial communication, glucose metabolism, and cellular adaptation to metabolic stress.
For Research Use Only (RUO)
Description
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino-acid mitochondrial-derived peptide investigated for its involvement in cellular energy regulation, metabolic signaling, and adaptive stress responses.
Encoded by a short open reading frame within the mitochondrial 12S ribosomal RNA region, MOTS-c represents an important research subject in mitochondrial biology and cellular metabolism.
Its discovery has contributed to scientific interest in mitochondrial-derived peptides as potential regulators of intracellular and intercellular communication.
Key Scientific Research Applications
1. Mitochondrial Communication Research
MOTS-c is investigated as a mitochondrial-derived signaling molecule potentially involved in communication between mitochondrial activity and nuclear regulatory pathways.
2. AMPK-Associated Metabolic Signaling
Experimental studies have associated MOTS-c with AMP-activated protein kinase (AMPK) signaling, a pathway involved in cellular energy sensing and metabolic adaptation.
3. Glucose Metabolism Research
Preclinical investigations examine MOTS-c-associated changes in glucose regulation, metabolic homeostasis, and cellular responses to altered energy availability.
4. Cellular Stress Response Research
Researchers investigate the potential role of MOTS-c in metabolic stress adaptation, including stress-associated nuclear localization and transcriptional regulation.
5. Metabolic Flexibility & Energy Homeostasis
MOTS-c is studied in experimental models exploring cellular metabolic flexibility, nutrient sensing, and energy balance.
Scientific Significance
MOTS-c represents an emerging area of mitochondrial peptide research. Its mitochondrial genetic origin and reported interactions with cellular metabolic pathways make it scientifically relevant to investigations of energy sensing, mitochondrial-nuclear communication, and stress-response biology.
Although preclinical findings are promising, the precise molecular mechanisms and broader biological significance of MOTS-c remain under investigation.
Research Use Only
For Research Use Only (RUO). Intended exclusively for laboratory research, analytical investigation, and scientific study.
Additional information
20mg, 40mg
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